J. Martin Bollinger All publications ( 37 ) Graci JD. Too K. Smidansky ED. Edathil JP. Barr EW. Harki DA. Galarraga JE. Bollinger JM. Peterson BR. Loakes D. Brown DM. Cameron CE. Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues. 2008 Mar. Antimicrob Agents Chemother. 52(3):971-9. Bollinger JM. Biochemistry. Electron relay in proteins. 2008 Jun 27. Science. 320(5884):1730-1. Jiang W. Saleh L. Barr EW. Xie J. Gardner MM. Krebs C. Bollinger JM. Branched activation- and catalysis-specific pathways for electron relay to the manganese/iron cofactor in ribonucleotide reductase from Chlamydia trachomatis. 2008 Aug 19. Biochemistry. 47(33):8477-84. Jiang W. Xie J. Nørgaard H. Bollinger JM. Krebs C. Rapid and quantitative activation of Chlamydia trachomatis ribonucleotide reductase by hydrogen peroxide. 2008 Apr 15. Biochemistry. 47(15):4477-83. Krebs C. Matthews ML. Jiang W. Bollinger JM. AurF from Streptomyces thioluteus and a possible new family of manganese/iron oxygenases. 2007 Sep 18. Biochemistry. 46(37):10413-8. Fujimori DG. Barr EW. Matthews ML. Koch GM. Yonce JR. Walsh CT. Bollinger JM. Krebs C. Riggs-Gelasco PJ. Spectroscopic evidence for a high-spin Br-Fe(IV)-oxo intermediate in the alpha-ketoglutarate-dependent halogenase CytC3 from Streptomyces. 2007 Nov 7. J Am Chem Soc. 129(44):13408-9. Neidig ML. Brown CD. Light KM. Fujimori DG. Nolan EM. Price JC. Barr EW. Bollinger JM. Krebs C. Walsh CT. Solomon EI. CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases. 2007 Nov 21. J Am Chem Soc. 129(46):14224-31. Yun D. Saleh L. García-Serres R. Chicalese BM. An YH. Huynh BH. Bollinger JM. Addition of oxygen to the diiron(II/II) cluster is the slowest step in formation of the tyrosyl radical in the W103Y variant of ribonucleotide reductase protein R2 from mouse. 2007 Nov 13. Biochemistry. 46(45):13067-73. Jiang W. Yun D. Saleh L. Barr EW. Xing G. Hoffart LM. Maslak MA. Krebs C. Bollinger JM. A manganese(IV)/iron(III) cofactor in Chlamydia trachomatis ribonucleotide reductase. 2007 May 25. Science. 316(5828):1188-91. National Institute of General Medical Sciences Sinnecker S. Svensen N. Barr EW. Ye S. Bollinger JM. Neese F. Krebs C. Spectroscopic and computational evaluation of the structure of the high-spin Fe(IV)-oxo intermediates in taurine: alpha-ketoglutarate dioxygenase from Escherichia coli and its His99Ala ligand variant. 2007 May 16. J Am Chem Soc. 129(19):6168-79. National Institute of General Medical Sciences Jiang W. Bollinger JM. Krebs C. The active form of Chlamydia trachomatis ribonucleotide reductase R2 protein contains a heterodinuclear Mn(IV)/Fe(III) cluster with S = 1 ground state. 2007 Jun 20. J Am Chem Soc. 129(24):7504-5. National Cancer Institute National Institute for Biomedical Imaging and Bioengineering National Institute of General Medical Sciences Krebs C. Galonić Fujimori D. Walsh CT. Bollinger JM. Non-Heme Fe(IV)-Oxo Intermediates. 2007 Jun 2. Acc Chem Res. . Jiang W. Hoffart LM. Krebs C. Bollinger JM. A manganese(IV)/iron(IV) intermediate in assembly of the manganese(IV)/iron(III) cofactor of Chlamydia trachomatis ribonucleotide reductase. 2007 Jul 31. Biochemistry. 46(30):8709-16. Mitić N. Clay MD. Saleh L. Bollinger JM. Solomon EI. Spectroscopic and electronic structure studies of intermediate X in ribonucleotide reductase R2 and two variants: a description of the FeIV-oxo bond in the FeIII-O-FeIV dimer. 2007 Jul 25. J Am Chem Soc. 129(29):9049-65. National Institute of General Medical Sciences Yun D. García-Serres R. Chicalese BM. An YH. Huynh BH. Bollinger JM. (Mu-1,2-peroxo)diiron(III/III) complex as a precursor to the diiron(III/IV) intermediate X in the assembly of the iron-radical cofactor of ribonucleotide reductase from mouse. 2007 Feb 20. Biochemistry. 46(7):1925-32. National Institute of General Medical Sciences Eser BE. Barr EW. Frantom PA. Saleh L. Bollinger JM. Krebs C. Fitzpatrick PF. Direct Spectroscopic Evidence for a High-Spin Fe(IV) Intermediate in Tyrosine Hydroxylase. 2007 Aug 23. J Am Chem Soc. . Bollinger JM. Krebs C. Enzymatic C-H activation by metal-superoxo intermediates. 2007 Apr. Curr Opin Chem Biol. 11(2):151-8. National Institute of Diabetes and Digestive and Kidney Diseases Hoffart LM. Barr EW. Guyer RB. Bollinger JM. Krebs C. Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase. 2006 Oct 3. Proc Natl Acad Sci U S A. 103(40):14738-43. National Institute of General Medical Sciences Xing G. Barr EW. Diao Y. Hoffart LM. Prabhu KS. Arner RJ. Reddy CC. Krebs C. Bollinger JM. Oxygen activation by a mixed-valent, diiron(II/III) cluster in the glycol cleavage reaction catalyzed by myo-inositol oxygenase. 2006 May 2. Biochemistry. 45(17):5402-12. Xing G. Hoffart LM. Diao Y. Prabhu KS. Arner RJ. Reddy CC. Krebs C. Bollinger JM. A coupled dinuclear iron cluster that is perturbed by substrate binding in myo-inositol oxygenase. 2006 May 2. Biochemistry. 45(17):5393-401. Yeh E. Cole LJ. Barr EW. Bollinger JM. Ballou DP. Walsh CT. Flavin Redox Chemistry Precedes Substrate Chlorination during the Reaction of the Flavin-Dependent Halogenase RebH. 2006 Jun 27. Biochemistry. 45(25):7904-7912. Saleh L. Bollinger JM. Cation mediation of radical transfer between Trp48 and Tyr356 during O2 activation by protein R2 of Escherichia coli ribonucleotide reductase: relevance to R1-R2 radical transfer in nucleotide reduction? 2006 Jul 25. Biochemistry. 45(29):8823-30. National Institute of General Medical Sciences Xing G. Diao Y. Hoffart LM. Barr EW. Prabhu KS. Arner RJ. Reddy CC. Krebs C. Bollinger JM. Evidence for C-H cleavage by an iron-superoxide complex in the glycol cleavage reaction catalyzed by myo-inositol oxygenase. 2006 Apr 18. Proc Natl Acad Sci U S A. 103(16):6130-5. Bollinger JM. Krebs C. Stalking intermediates in oxygen activation by iron enzymes: motivation and method. 2006 Apr. J Inorg Biochem. 100(4):586-605. National Institute of General Medical Sciences Price JC. Barr EW. Hoffart LM. Krebs C. Bollinger JM. Kinetic dissection of the catalytic mechanism of taurine:alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli. 2005 Jun 7. Biochemistry. 44(22):8138-47. National Institute of General Medical Sciences Krebs C. Price JC. Baldwin J. Saleh L. Green MT. Bollinger JM. Rapid freeze-quench 57Fe Mössbauer spectroscopy: monitoring changes of an iron-containing active site during a biochemical reaction. 2005 Feb 21. Inorg Chem. 44(4):742-57. National Institute of General Medical Sciences Behshad E. Parkin SE. Bollinger JM. Mechanism of cysteine desulfurase Slr0387 from Synechocystis sp. PCC 6803: kinetic analysis of cleavage of the persulfide intermediate by chemical reductants. 2004 Sep 28. Biochemistry. 43(38):12220-6. Tirupati B. Vey JL. Drennan CL. Bollinger JM. Kinetic and structural characterization of Slr0077/SufS, the essential cysteine desulfurase from Synechocystis sp. PCC 6803. 2004 Sep 28. Biochemistry. 43(38):12210-9. National Institute of General Medical Sciences Saleh L. Krebs C. Ley BA. Naik S. Huynh BH. Bollinger JM. Use of a chemical trigger for electron transfer to characterize a precursor to cluster X in assembly of the iron-radical cofactor of Escherichia coli ribonucleotide reductase. 2004 May 25. Biochemistry. 43(20):5953-64. National Institute of General Medical Sciences Saleh L. Kelch BA. Pathickal BA. Baldwin J. Ley BA. Bollinger JM. Mediation by indole analogues of electron transfer during oxygen activation in variants of Escherichia coli ribonucleotide reductase R2 lacking the electron-shuttling tryptophan 48. 2004 May 25. Biochemistry. 43(20):5943-52. National Institute of General Medical Sciences Price JC. Barr EW. Glass TE. Krebs C. Bollinger JM. Evidence for hydrogen abstraction from C1 of taurine by the high-spin Fe(IV) intermediate detected during oxygen activation by taurine:alpha-ketoglutarate dioxygenase (TauD). 2003 Oct 29. J Am Chem Soc. 125(43):13008-9. Baldwin J. Krebs C. Saleh L. Stelling M. Huynh BH. Bollinger JM. Riggs-Gelasco P. Structural characterization of the peroxodiiron(III) intermediate generated during oxygen activation by the W48A/D84E variant of ribonucleotide reductase protein R2 from Escherichia coli. 2003 Nov 18. Biochemistry. 42(45):13269-79. National Center for Research Resources National Institute of General Medical Sciences Price JC. Barr EW. Tirupati B. Bollinger JM. Krebs C. The first direct characterization of a high-valent iron intermediate in the reaction of an alpha-ketoglutarate-dependent dioxygenase: a high-spin FeIV complex in taurine/alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli. 2003 Jun 24. Biochemistry. 42(24):7497-508. Yun D. Krebs C. Gupta GP. Iwig DF. Huynh BH. Bollinger JM. Facile electron transfer during formation of cluster X and kinetic competence of X for tyrosyl radical production in protein R2 of ribonucleotide reductase from mouse. 2002 Jan 22. Biochemistry. 41(3):981-90. National Institute of General Medical Sciences Baldwin J. Voegtli WC. Khidekel N. Moënne-Loccoz P. Krebs C. Pereira AS. Ley BA. Huynh BH. Loehr TM. Riggs-Gelasco PJ. Rosenzweig AC. Bollinger JM. Rational reprogramming of the R2 subunit of Escherichia coli ribonucleotide reductase into a self-hydroxylating monooxygenase. 2001 Jul 25. J Am Chem Soc. 123(29):7017-30. National Institute of General Medical Sciences Parkin SE. Chen S. Ley BA. Mangravite L. Edmondson DE. Huynh BH. Bollinger JM. Electron injection through a specific pathway determines the outcome of oxygen activation at the diiron cluster in the F208Y mutant of Escherichia coli ribonucleotide reductase protein R2. 1998 Jan 27. Biochemistry. 37(4):1124-30. National Institute of General Medical Sciences Lin CH. Kwon DS. Bollinger JM. Walsh CT. Evidence for a glutathionyl-enzyme intermediate in the amidase activity of the bifunctional glutathionylspermidine synthetase/amidase from Escherichia coli. 1997 Dec 2. Biochemistry. 36(48):14930-8. National Institute of General Medical Sciences