Thomas P. Loughran
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Academic title Professor of Medicine; Director of Penn State Cancer Institute
College College of Medicine
Campuses Penn State Milton S. Hershey Medical Center
Department Medicine
Graduate programs
Email Phone
  tloughran@psu.edu
  717 531 4034
 
Educational background
  M.D., Hahnemann University School of Medicine, 1979
Internship, Thomas Jefferson University Hospital
Residency, Thomas Jefferson University Hospital
Fellowship, Fred Hutchinson Cancer Research Center, University of Washington
Research interests
 

Large granular lymphocyte (LGL) leukemia


Retrovirus infections


Cellular immunity

Areas of expertise
 
ApoptosisMyelodysplastic Syndromes
T-Lymphocytes, CytotoxicKiller Cells, Natural
Hematologic NeoplasmsHuman T-lymphotropic virus 1
Leukemia, Prolymphocytic, T-CellBone Marrow Transplantation
HTLV-I InfectionsHTLV-II Infections
Anemia, AplasticGene Expression Regulation
HIV InfectionsInterferon Type II
Interleukin-2Morphine
Postoperative ComplicationsFracture Fixation, Intramedullary
Knee ProsthesisFemoral Fractures
Publication author name
  Loughran TP Jr
Loughran TP
Select publications
  Liu JH. Wei S. Lamy T. Li Y. Epling-Burnette PK. Djeu JY. Loughran TP. Blockade of Fas-dependent apoptosis by soluble Fas in LGL leukemia. 2002 Aug 15. Blood. 100(4):1449-53.
National Cancer Institute
Epling-Burnette PK. Liu JH. Catlett-Falcone R. Turkson J. Oshiro M. Kothapalli R. Li Y. Wang JM. Yang-Yen HF. Karras J. Jove R. Loughran TP. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. 2001 Feb. J Clin Invest. 107(3):351-62.
National Cancer Institute
Loughran TP. Hadlock KG. Yang Q. Perzova R. Zambello R. Semenzato G. Foung SK. Poiesz BJ. Seroreactivity to an envelope protein of human T-cell leukemia/lymphoma virus in patients with CD3- (natural killer) lymphoproliferative disease of granular lymphocytes. 1997 Sep 1. Blood. 90(5):1977-81.
National Cancer Institute
National Institute on Drug Abuse
National Heart, Lung, and Blood Institute
Loughran TP. Clonal diseases of large granular lymphocytes. 1993 Jul 1. Blood. 82(1):1-14.
National Cancer Institute
also ...
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