Interleukin-1
Description
  A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
Synonyms
  IL-1
Lymphocyte-Activating Factor
Epidermal Cell Derived Thymocyte-Activating Factor
Interleukin I
Macrophage Cell Factor
T Helper Factor
Epidermal Cell Derived Thymocyte Activating Factor
Interleukin 1
Lymphocyte Activating Factor
Parents
  Monokines
Interleukins
Children
  Interleukin-1alpha
Interleukin-1beta
See Also
  Receptors, Interleukin-1
Experts
  Robert N. Cooney
Laurence M. Demers
Jidong Fang
Robert A. Frost
Gavin R. Graff
Douglas Granger
Charles H. Lang
Andrea Mastro
Jan M. McAllister
David S. Phelps
Wiley W. Souba
Shao-Cong Sun
Elizabeth Susman
Thomas C. Vary
Margaret M. Wojnar
Tree Numbers
  D12.644.276.374.465.501
D12.644.276.374.500.400
D12.776.467.374.465.501
D12.776.467.374.500.400
D23.529.374.465.501
D23.529.374.500.400
MeSH ID
  D007375

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