Interleukin-12
Description
  A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.
Synonyms
  Edodekin Alfa
IL-12
Natural Killer Cell Stimulatory Factor
Cytotoxic Lymphocyte Maturation Factor
IL 12
IL-12 p70
IL12
Interleukin 12
Interleukin-12 p70
Interleukin 12 p70
p70, Interleukin-12
Parents
  Interleukins
Children
  Interleukin-12 Subunit p35
Interleukin-12 Subunit p40
See Also
  Immunity, Cellular
Actions
  Adjuvants, Immunologic
Angiogenesis Inhibitors
Experts
  Michael J. Chorney
Pamela Correll
Walter A. Koltun
Lisa S. Poritz
Tree Numbers
  D12.644.276.374.465.512
D12.776.467.374.465.512
D23.529.374.465.512
MeSH ID
  D018664

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