 |  | |
|
Description |
| |
A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members.
|
|
|
Synonyms |
| |
HER-2 Proto-Oncogene Protein
Proto-Oncogene Protein HER-2
Proto-Oncogene Protein p185(neu)
Receptor, neu
c-erbB-2 Protein
erbB-2 Proto-Oncogene Protein
erbB-2 Receptor Protein-Tyrosine Kinase
neu Proto-Oncogene Protein
neu Receptor
Oncogene Protein HER-2
Proto-Oncogene Proteins c-erbB-2
Receptors, erbB-2
p185(c-neu)
HER 2 Proto Oncogene Protein
Oncogene Protein HER 2
Proto Oncogene Protein HER 2
Proto Oncogene Proteins c erbB 2
Proto-Oncogene Protein, HER-2
Proto-Oncogene Protein, erbB-2
Proto-Oncogene Protein, neu
Receptor, erbB 2
Receptors, erbB 2
c erbB 2 Protein
erbB 2 Proto Oncogene Protein
erbB 2 Receptor Protein Tyrosine Kinase
erbB-2 Receptor
erbB-2 Receptors
neu Proto Oncogene Protein
|
|
|
Parents | |
|
|
See Also | |
|
|
Experts | |
|
|
Tree Numbers |
| |
D08.811.913.696.620.682.725.400.150
D12.776.543.750.060.374
D12.776.543.750.750.400.350
D12.776.624.664.700.642
D23.101.840.642
|
|
|
MeSH ID | |
|
|
|
|
|
