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Description |
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Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.
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Synonyms |
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gamma-Aminobutyric Acid Modulators
GABAergic Modulators
Acid Modulators, gamma-Aminobutyric
Modulators, GABA
Modulators, GABAergic
Modulators, gamma-Aminobutyric Acid
gamma Aminobutyric Acid Modulators
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Examples |
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Experts |
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Tree Numbers |
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D27.505.519.625.240.500
D27.505.696.577.240.500
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