Polymorphism, Single-Stranded Conformational
Description
  Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
Synonyms
  SSCP
Single-Stranded Conformational Polymorphism
Conformational Polymorphism, Single-Stranded
Conformational Polymorphisms, Single-Stranded
Polymorphism, Single Stranded Conformational
Polymorphisms, Single-Stranded Conformational
Single Stranded Conformational Polymorphism
Single-Stranded Conformational Polymorphisms
Parents
  Polymorphism, Genetic
Experts
  Christopher Herzog
Tree Numbers
  G13.920.795.600
MeSH ID
  D018807

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