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Description |
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Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
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Synonyms |
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GPIIb-IIIa Receptors
Integrin alphaIIbbeta3
Glycoproteins IIb-IIIa
Integrin alpha-IIb beta-3
GPIIb IIIa Receptors
Glycoproteins IIb IIIa
Integrin alpha IIb beta 3
Platelet Glycoprotein GPIIb IIIa Complex
Receptors, GPIIb-IIIa
alphaIIbbeta3, Integrin
beta-3, Integrin alpha-IIb
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See Also |
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Experts |
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Tree Numbers |
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D12.776.395.550.625.785
D12.776.543.550.625.785
D12.776.543.750.705.408.460.700
D12.776.543.750.705.675.784
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