Cytochrome P-450 CYP2D6
Description
  A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.
Synonyms
  CYP2D6
Debrisoquine 4-Hydroxylase
Debrisoquine Hydroxylase
CYP 2D6
Cytochrome P450 2D6
Debrisoquine 4-Monooxygenase
Imipramine 2-Hydroxylase
Sparteine Monooxygenase
2-Hydroxylase, Imipramine
4-Hydroxylase, Debrisoquine
4-Monooxygenase, Debrisoquine
CYP2D6, Cytochrome P-450
Cytochrome P 450 CYP2D6
Debrisoquine 4 Hydroxylase
Debrisoquine 4 Monooxygenase
Hydroxylase, Debrisoquine
Imipramine 2 Hydroxylase
Monooxygenase, Sparteine
P-450 CYP2D6, Cytochrome
P450 2D6, Cytochrome
Parents
  Aryl Hydrocarbon Hydroxylases
Experts
  Piotr Janicki
H. Gregg Schuler
Tree Numbers
  D08.244.453.040.944
D08.811.682.690.708.170.040.555
D12.776.422.220.453.040.888
MeSH ID
  D019389
also ...
 Publications