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Description |
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A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, the kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the inhibition of protein synthesis.
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Synonyms |
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Protein Kinase PKR
Protein Kinase, RNA Activated
RNA-Dependent Protein Kinase
p68 Kinase
DAI Protein Kinase
DSRNA-Dep Protein Kinase
Double Stranded RNA-Dependent Kinase (dsl)
Double Stranded RNA-Dependent eIF-2 alpha Protein Kinase
Eukaryotic Initiation Factor 2alpha Kinase
Heme Controlled Repressor
Heme-Controlled Inhibitor
Heme-Controlled Translational Repressor
Heme-Regulated eIF-2alpha Kinase
Hemin Controlled Repressor
Hemin-Controlled Translational Repressor
P68 Protein Kinase
Self-Phosphorylating Protein Kinase
TIK Kinase
dsRNA-Activated Inhibitor
eIF-2alpha Kinase
eRF, eIF-2 Recycling Factor
p65 Kinase
Controlled Repressor, Heme
Controlled Repressor, Hemin
DSRNA Dep Protein Kinase
Double Stranded RNA Dependent eIF 2 alpha Protein Kinase
Heme Controlled Inhibitor
Heme Controlled Translational Repressor
Heme Regulated eIF 2alpha Kinase
Hemin Controlled Translational Repressor
Inhibitor, Heme-Controlled
Inhibitor, dsRNA-Activated
Kinase PKR, Protein
Kinase, DAI Protein
Kinase, DSRNA-Dep Protein
Kinase, Heme-Regulated eIF-2alpha
Kinase, P68 Protein
Kinase, RNA-Dependent Protein
Kinase, Self-Phosphorylating Protein
Kinase, TIK
Kinase, eIF-2
Kinase, eIF-2alpha
Kinase, p65
Kinase, p68
PKR, Protein Kinase
Protein Kinase, DAI
Protein Kinase, DSRNA-Dep
Protein Kinase, P68
Protein Kinase, RNA-Dependent
Protein Kinase, Self-Phosphorylating
RNA Dependent Protein Kinase
Repressor, Heme Controlled
Repressor, Heme-Controlled Translational
Repressor, Hemin Controlled
Repressor, Hemin-Controlled Translational
Self Phosphorylating Protein Kinase
Translational Repressor, Heme-Controlled
Translational Repressor, Hemin-Controlled
dsRNA Activated Inhibitor
eIF 2 Kinase
eIF 2alpha Kinase
eIF-2alpha Kinase, Heme-Regulated
eRF, eIF 2 Recycling Factor
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Experts | |
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Tree Numbers |
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D08.811.913.696.620.682.700.300
D12.644.360.275
D12.776.476.275
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MeSH ID | |
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