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Description |
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A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)
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Synonyms |
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MPTP Neurotoxicity Syndrome
MPTP-Induced Degeneration of the Striatum
MPTP-Induced Parkinsonism
Neurotoxicity Syndrome, MPTP
Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
MPTP Induced Degeneration of the Striatum
MPTP Induced Parkinsonism
MPTP Neurotoxicity Syndromes
Neurotoxicity Syndromes, MPTP
Parkinsonism, MPTP-Induced
Poisoning, MPTP
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Tree Numbers |
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C10.228.140.079.862.800.300
C10.228.662.600.700.250
C10.720.606
C21.613.705.400
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