Isoprostanes
Description
  A series of prostaglandin-like compounds that are produced by the attack of free-radical species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES. Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. Although these compounds resemble enzymatically synthesized prostaglandins their stereoisometric arrangement is usually different than the "naturally occurring" compounds.
Synonyms
  Isoprostane
Parents
  Arachidonic Acids
Fatty Acids, Unsaturated
Children
  F2-Isoprostanes
Experts
  Terryl Hartman
Tree Numbers
  D10.251.355.255.100.375
D10.251.355.411
MeSH ID
  D028421

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