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Description |
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An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3 is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is also abundant in vascular smooth muscle and endothelial cells, and in some tumor cells, where it is involved in angiogenesis and cell migration. Although often referred to as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS, VITRONECTIN).
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Synonyms |
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Integrin alpha-v beta-3
Receptors, alpha-v beta-3 Integrin
Vitronectin Receptor
alpha-v beta-3 Integrin Receptors
Integrin alpha v beta 3
Receptor, Vitronectin
Receptors, alpha v beta 3 Integrin
alpha v beta 3 Integrin Receptors
alpha-v beta-3, Integrin
alphaVbeta3, Integrin
beta-3, Integrin alpha-v
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Tree Numbers |
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D12.776.395.550.625.439
D12.776.543.550.625.439
D12.776.543.750.705.408.460.870.500
D12.776.543.750.705.675.541
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