Proteasome Endopeptidase Complex
Description
  A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.
Synonyms
  20S Proteasome
Ingensin
Macropain
Macroxyproteinase
Multicatalytic Endopeptidase Complex
Multicatalytic Proteinase
Prosome
Proteasome
Complex, Multicatalytic Endopeptidase
Complex, Proteasome Endopeptidase
Endopeptidase Complex, Multicatalytic
Endopeptidase Complex, Proteasome
Proteasome, 20S
Proteinase, Multicatalytic
Parents
  Multienzyme Complexes
Peptide Hydrolases
See Also
  Ubiquitin-Protein Ligase Complexes
Experts
  Robert A. Frost
Leonard S. Jefferson, Jr.
Charles H. Lang
Craig Meyers
Thomas C. Vary
Jin-Ming Yang
Tree Numbers
  D05.500.562.500
D08.811.277.656.918
D08.811.600.730
MeSH ID
  D046988

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