Glucose kinetic responses to protein supplementation and exogenous somatotropin in late gestation dairy cows.
Journal
  Journal of dairy science.
Citation
  J Dairy Sci. 82(6):1274-81
Publication date
  1999 Jun
Authors
  Putnam DE
Varga GA
Green MH
Investigators
  Michael Green
Gabriella Varga
MeSH headings
  Blood Glucose
Cattle
Dietary Proteins
Gestational Age
Growth Hormone
MeSH qualifiers
  metabolism
blood
administration & dosage
pharmacology
Abstract
  Glucose kinetics were measured in late gestation multiparous Holstein dairy cows fed diets with different amounts of dietary crude protein (13.3 vs. 17.8%), with and without exogenous somatotropin. The trial was conducted as a completely randomized design; 35 cows were used in the final analysis. Kinetic measurements were made using the single injection technique with uniformly labeled 13C-labeled glucose. A diet that contained 17.8% crude protein appeared to increase glucose utilization without a corresponding increase in supply. The evidence was an increased rate of glucose disposal. In contrast, exogenous bovine somatotropin (Posilac, Monsanto Co., St. Louis, MO) appeared to enhance glucose conservation, as indicated by a tendency for a decreased fractional catabolic rate and an increased glucose pool size. Somatotropin appeared to modify glucose metabolism in a pattern favorable for supporting terminal fetal development and lactogenesis and for maintaining or enhancing maternal glycemia. The latter pattern could have implications for improving the health of periparturient dairy cows.
Medline ID
  99314091