Transposable elements as a molecular evolutionary force.
Journal
  Annals of the New York Academy of Sciences.
Citation
  Ann N Y Acad Sci. 870:251-64
Publication date
  1999 May 18
Authors
  Fedoroff NV
Investigators
  Nina Fedoroff
MeSH headings
  DNA Transposable Elements
Evolution, Molecular
Abstract
  This essay addresses the paradoxes of the complex and highly redundant genomes. The central theses developed are that: (1) the distinctive feature of complex genomes is the existence of epigenetic mechanisms that permit extremely high levels of both tandem and dispersed redundancy; (2) the special contribution of transposable elements is to modularize the genome; and (3) the labilizing forces of recombination and transposition are just barely contained, giving a dynamic genetic system of ever increasing complexity that verges on the chaotic.
Medline ID
  99343977