CLENCH: a program for calculating Cluster ENriCHment using the Gene Ontology.
Journal
  Bioinformatics (Oxford, England)
Citation
  Bioinformatics. 20(7):1196-7
Publication date
  2004 May 1
Authors
  Shah NH
Fedoroff NV
Investigators
  Nina Fedoroff
MeSH headings
  Abstracting and Indexing as Topic
Arabidopsis
Gene Expression Profiling
Sequence Alignment
Software
MeSH qualifiers
  methods
genetics
Abstract
  SUMMARY: Analysis of microarray data most often produces lists of genes with similar expression patterns, which are then subdivided into functional categories for biological interpretation. Such functional categorization is most commonly accomplished using Gene Ontology (GO) categories. Although there are several programs that identify and analyze functional categories for human, mouse and yeast genes, none of them accept Arabidopsis thaliana data. In order to address this need for A.thaliana community, we have developed a program that retrieves GO annotations for A.thaliana genes and performs functional category analysis for lists of genes selected by the user. AVAILABILITY: http://www.personal.psu.edu/nhs109/Clench