A rapid screening battery to identify frontal dysfunction in patients with ALS.
Journal
  Neurology.
Citation
  Neurology. 67(11):2070-2
Publication date
  2006 Dec 12
Authors
  Flaherty-Craig C
Eslinger P
Stephens B
Simmons Z
Investigators
  Paul N. Eslinger
Zachary Simmons
MeSH headings
  Amyotrophic Lateral Sclerosis
Cognition Disorders
Mass Screening
MeSH qualifiers
  psychology
diagnosis
methods
Abstract
  We studied the relationship between verbal associative fluency, verbal abstract reasoning, and judgment in ALS using a 20-minute screening evaluation. Deficiencies in these measures were found in 20.0%, 18.6%, and 35.7% of patients with limb-onset ALS and in 37.5%, 25.0%, and 60.0% of patients with bulbar-onset ALS. This simple screen identifies deficits that affect discussions of treatment interventions and end-of-life issues.