Quorum sensing enhances the stress response in Vibrio cholerae.
Journal
  American journal of physiology. Endocrinology and metabolism.
Structure (London, England)
Applied and environmental microbiology.
Citation
  Appl Environ Microbiol. 73(11):3742-6
Publication date
  2007 Jun
Authors
  Joelsson A
Kan B
Zhu J
Investigators
  Jiyue Zhu
Grant agencies
  National Institute of Child Health and Human Development
National Institute of Mental Health
National Center for Research Resources
National Institute of Allergy and Infectious Diseases
Grants
  NIAID K22 AI060715
NIAID R01 AI072479
MeSH headings
  Gene Expression Regulation, Bacterial
Microbial Viability
Oxidative Stress
Quorum Sensing
Vibrio cholerae
MeSH qualifiers
  physiology
Abstract
  Vibrio cholerae lives in aquatic environments and causes cholera. Here, we show that quorum sensing enhances V. cholerae viability under certain stress conditions by upregulating the expression of RpoS, and this regulation acts through HapR, suggesting that a quorum-sensing-enhanced stress response plays a role in V. cholerae environmental survival.