Reversible decrease of fluoride resistant acid phosphatase-positive neurons after herpes simplex virus infection.
Journal
  Neuroscience letters.
Citation
  Neurosci Lett. 130(1):85-8
Publication date
  1991 Sep 2
Authors
  Tenser RB
Viselli AL
Savage DH
Investigators
  Richard B. Tenser
Grant agencies
  National Institute of Neurological Disorders and Stroke
Grants
  NINDS NS20684
MeSH headings
  Acid Phosphatase
Fluorides
Herpes Simplex
Neurons
MeSH qualifiers
  metabolism
pharmacology
pathology
enzymology
Abstract
  Herpes simplex virus (HSV) frequently infects human sensory ganglion neurons, and similar infections have been reported in experimental animals. Reported here is an investigation of in vivo neuronal function after HSV infection. It was observed that the proportion of fluoride resistant acid phosphatase (FRAP)-positive trigeminal ganglion neurons was decreased for several months after experimental infection of mice, and it is suggested that other neuronal functions may also be altered by HSV.
Medline ID
  92086177